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	Provedor de dados BJMBR (7) Autor Brandão,M.L. (7) Guimarães,F.S. (2) Albrechet-Souza,L. (1) Andreatini,R. (1) Bassi,G.S. (1) Blanchard,C. (1) Blanchard,R. (1) Brenes,J.C. (1) Broiz,A.C. (1) Carobrez,A.P. (1) Carvalho,M.C. (1) Cirilo-Júnior,G. (1) Da Cunha,C. (1) Del Bel,E.A. (1) Graeff,F.G. (1) Griebel,G. (1) Handley,S.L. (1) Jenck,F. (1) Leite,J.R. (1) Masson,S. (1) Mais... Palavra-chave Amygdala (2) Anxiety (2) Fear (2) Serotonin (2) Social isolation (2) 5-HT (1) Active avoidance (1) Animal models (1) Anxiolytics (1) Aversive stimuli (1) Benzodiazepines (1) Defense reaction (1) Dopamine (1) Dorsal periaqueductal gray (1) Elevated plus maze (1) Elevated plus-maze (1) Escape (1) Exploratory behavior (1) Freezing (1) Hippocampus (1) Mais... Tipo do documento Info:eu-repo/semantics/article (6) Info:eu-repo/semantics/other (1) Ano 2012 (1) 2005 (2) 2003 (1) 2001 (1) 1998 (1) 1997 (1) Mais... País Brazil (7) Idioma Inglês (7)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 7 Primeira ... 1 ... Última Anatomical connections of the periaqueductal gray: specific neural substrates for different kinds of fear BJMBR Vianna,D.M.L.; Brandão,M.L.. The periaqueductal gray (PAG) has been traditionally considered to be an exit relay for defensive responses. Functional mapping of its subdivisions has advanced our knowledge of this structure, but synthesis remains difficult mainly because results from lesion and stimulation studies have not correlated perfectly. After using a strategy that combined both techniques and a reevaluation of the available literature on PAG function and connections, we propose here that freezing could be mediated by different PAG subdivisions depending on the presence of immediate danger or exposure to related signaling cues. These subdivisions are separate functional entities with distinct descending and ascending connections that are likely to play a role in different... Tipo: Info:eu-repo/semantics/article Palavras-chave: Periaqueductal gray; Defense reaction; Fear; Escape; Freezing; Periaqueductal gray columns. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000500002 Changes in the biogenic amine content of the prefrontal cortex, amygdala, dorsal hippocampus, and nucleus accumbens of rats submitted to single and repeated sessions of the elevated plus-maze test BJMBR Carvalho,M.C.; Albrechet-Souza,L.; Masson,S.; Brandão,M.L.. It has been demonstrated that exposure to a variety of stressful experiences enhances fearful reactions when behavior is tested in current animal models of anxiety. Until now, no study has examined the neurochemical changes during the test and retest sessions of rats submitted to the elevated plus maze (EPM). The present study uses a new approach (HPLC) by looking at the changes in dopamine and serotonin levels in the prefrontal cortex, amygdala, dorsal hippocampus, and nucleus accumbens in animals upon single or double exposure to the EPM (one-trial tolerance). The study involved two experiments: i) saline or midazolam (0.5 mg/kg) before the first trial, and ii) saline or midazolam before the second trial. For the biochemical analysis a control group... Tipo: Info:eu-repo/semantics/article Palavras-chave: One-trial tolerance; Dopamine; Serotonin; Prefrontal cortex; Amygdala; Hippocampus. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001200014 Involvement of midbrain tectum neurokinin-mediated mechanisms in fear and anxiety BJMBR Brenes,J.C.; Broiz,A.C.; Bassi,G.S.; Schwarting,R.K.W.; Brandão,M.L.. Electrical stimulation of midbrain tectum structures, particularly the dorsal periaqueductal gray (dPAG) and inferior colliculus (IC), produces defensive responses, such as freezing and escape behavior. Freezing also ensues after termination of dPAG stimulation (post-stimulation freezing). These defensive reaction responses are critically mediated by γ-aminobutyric acid and 5-hydroxytryptamine mechanisms in the midbrain tectum. Neurokinins (NKs) also play a role in the mediation of dPAG stimulation-evoked fear, but how NK receptors are involved in the global processing and expression of fear at the level of the midbrain tectum is yet unclear. The present study investigated the role of NK-1 receptors in unconditioned defensive behavior induced by electrical... Tipo: Info:eu-repo/semantics/article Palavras-chave: Neurokinin-1 receptors; Dorsal periaqueductal gray; Spantide; Unconditioned fear; Elevated plus maze; Ultrasonic vocalizations. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000400009 Paradoxical increase of exploratory behavior in the elevated plus-maze by rats exposed to two kinds of aversive stimuli BJMBR Morato,S.; Brandão,M.L.. Albino rats were submitted to a 24-h period of social isolation (individual housing) combined with 0, 1, 2 or 3 twenty-four-hour periods of exposure to different vivaria (novelty) and tested in the elevated plus-maze. Results, reported as mean ± SEM for N = 12, show that the time (in seconds) spent in the open arms by rats exposed to novelty for 0, 1, 2 and 3 days was 28.3 ± 4.4, 31.6 ± 3.2, 29.1 ± 3.5 and 25.0 ± 3.3, respectively, when grouped in the same vivarium; 29.6 ± 2.7, 7.6 ± 2.1, 9.6 ± 4.4 and 28.5 ± 3.7 when grouped in different vivaria; 2.9 ± 1.1, 1.8 ± 1.0, 2.7 ± 1.1 and 0 ± 0 when isolated in the same vivarium, and 2.6 ± 1.1, 31.5 ± 8.2, 24.8 ± 4.2 and 0 ± 0 when isolated in different vivaria. The number of entries into the open and closed... Tipo: Info:eu-repo/semantics/article Palavras-chave: Elevated plus-maze; Social isolation; Novelty; Anxiety; Exploratory behavior; Aversive stimuli. Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000900010 Routine post-weaning handling of rats prevents isolation rearing-induced deficit in prepulse inhibition BJMBR Rosa,M.L.N.M.; Silva,R.C.B.; Moura-de-Carvalho,F.T.; Brandão,M.L.; Guimarães,F.S.; Del Bel,E.A.. Rats reared under isolation conditions from weaning present a number of behavioral changes compared to animals reared under social conditions (group housing). These changes include deficits in prepulse inhibition (PPI) of the startle reflex to a loud sound. PPI refers to the reduction of the magnitude of the startle reflex when a relatively weak stimulus (the prepulse) precedes by an appropriate time interval the intense startle-elicing stimulus (the pulse). PPI is useful for studying sensorimotor integration. The present study evaluated the effect of handling on the impairment of PPI induced by isolation-rearing. Male Wistar rats (N = 11-15/group) were housed in groups (5 per cage and handled three times a week) or isolated (housed individually) since... Tipo: Info:eu-repo/semantics/other Palavras-chave: Stress; Rat; Schizophrenia; Social isolation; Prepulse inhibition; Locomotor activity. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001100018 Signaled two-way avoidance learning using electrical stimulation of the inferior colliculus as negative reinforcement: effects of visual and auditory cues as warning stimuli BJMBR Troncoso,A.C.; Cirilo-Júnior,G.; Sandner,G.; Brandão,M.L.. The inferior colliculus is a primary relay for the processing of auditory information in the brainstem. The inferior colliculus is also part of the so-called brain aversion system as animals learn to switch off the electrical stimulation of this structure. The purpose of the present study was to determine whether associative learning occurs between aversion induced by electrical stimulation of the inferior colliculus and visual and auditory warning stimuli. Rats implanted with electrodes into the central nucleus of the inferior colliculus were placed inside an open-field and thresholds for the escape response to electrical stimulation of the inferior colliculus were determined. The rats were then placed inside a shuttle-box and submitted to a two-way... Tipo: Info:eu-repo/semantics/article Palavras-chave: Inferior colliculus; Active avoidance; Selective attention. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000300011 The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis BJMBR Andreatini,R.; Blanchard,C.; Blanchard,R.; Brandão,M.L.; Carobrez,A.P.; Griebel,G.; Guimarães,F.S.; Handley,S.L.; Jenck,F.; Leite,J.R.; Rodgers,J.; Schenberg,L.C.; Da Cunha,C.; Graeff,F.G.. This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else, and what aspects of clinical anxiety are reproduced by animal models. Concerning the first issue, most participants agreed that generalized anxiety and panic disorder are different on the basis of clinical manifestations, drug response and animal models. Also, underlying brain structures, neurotransmitter modulation and hormonal changes seem to involve important differences. It is also common knowledge that existing animal models generate different types of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Panic; Anxiety; Fear; Anxiolytics; 5-HT; Benzodiazepines; Serotonin; Amygdala; Periaqueductal gray matter; Animal models. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200001 Registros recuperados: 7 Primeira ... 1 ... Última

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